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1: Lancet. 1981 Apr 18;1(8225):862-5.
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Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares.

Sullivan CE, Issa FG, Berthon-Jones M, Eves L.

Five patients with severe obstructive sleep apnoea were treated with continuous positive airway pressure (CPAP) applied via a comfortable nose mask through the nares. Low levels of pressure (range 4.5-10 cm H2O) completely prevented upper airway occlusion during sleep in each patient and allowed an entire night of uninterrupted sleep. Continuous positive airway pressure applied in this manner provides a pneumatic splint for the nasopharyngeal airway and is a safe, simple treatment for the obstructive sleep apnoea syndrome.

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PMID: 6112294 [PubMed - indexed for MEDLINE]