Nonlinear Biomedical Physics


Open Access Research

Simple fractal method of assessment of histological images for application in medical diagnostics

Wlodzimierz Klonowski*, Robert Stepien and Pawel Stepien

Author Affiliations

Lab. of Biosignal Analysis Fundamentals, Nalecz Institute of Biocybernetics and Biomedical Engineering Polish Academy of Sciences, Warsaw, Poland

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Nonlinear Biomedical Physics 2010, 4:7 doi:10.1186/1753-4631-4-7

Published: 6 December 2010

Abstract

We propose new method of assessment of histological images for medical diagnostics. 2-D image is preprocessed to form 1-D landscapes or 1-D signature of the image contour and then their complexity is analyzed using Higuchi's fractal dimension method. The method may have broad medical application, from choosing implant materials to differentiation between benign masses and malignant breast tumors.