Nonlinear Biomedical Physics


Open Access Debate

On fractional order models for Hepatitis C

E Ahmed1* and H A El-Saka2

Author Affiliations

1 Mathematics Department, Faculty of Science, Mansoura University, 35516, Mansoura, Egypt

2 Mathematics Department, Faculty of Science, Mansoura University, 34517, New Damietta, Egypt

For all author emails, please log on.

Nonlinear Biomedical Physics 2010, 4:1 doi:10.1186/1753-4631-4-1

Published: 18 March 2010

Abstract

In this paper we present a fractional order generalization of Perelson et al. basic hepatitis C virus (HCV) model including an immune response term. We argue that fractional order equations are more suitable than integer order ones in modeling complex systems which include biological systems. The model is presented and discussed. Also we argue that the added immune response term represents some basic properties of the immune system and that it should be included to study longer term behavior of the disease.